Kodi Machubu Otolera Magazi a EDTA Ndi Chiyani Ndipo Amagwiritsidwa Ntchito Motani?

Pakuyezetsa zamankhwala ndi kuwunika kwachipatala ndi chithandizo,Machubu otolera magazi a EDTA, monga zofunikira zogulitsira zosonkhanitsira magazi, zimagwira ntchito yofunika kwambiri potsimikizira kukhulupirika kwa zitsanzo ndi kuyesedwa kolondola. M'nkhaniyi, tisanthula mwatsatanetsatane "woyang'anira wosawonekayo" uyu pazachipatala kuchokera kumatanthauzo, kagayidwe kamitundu, mfundo ya anticoagulation, cholinga choyesa ndikugwiritsa ntchito muyezo.

Ndi chiyanichubu chotolera magazi cha EDTA?

Chubu chotolera magazi cha EDTA ndi mtundu wa chubu chosonkhanitsira magazi chomwe chili ndi Ethylene Diamine Tetraacetic Acid kapena mchere wake, womwe umagwiritsidwa ntchito makamaka potolera zitsanzo za magazi ndi mankhwala oletsa kukomoka. EDTA imatha kuletsa kukomoka kwa ma coagulation poyesa ma ayoni a calcium m'magazi, kuti magazi azikhala amadzimadzi kwa nthawi yayitali, ndikupereka zitsanzo zokhazikika zoyezetsa mayendedwe amagazi ndi ma cell biology. Amapereka zitsanzo zokhazikika zamachitidwe amagazi, biology yama cell ndi mayeso ena.

Monga gawo lofunikira lamankhwala ophera mankhwala, machubu osonkhanitsira magazi a EDTA akuyenera kutsatira muyezo wadziko lonse wa "zotengera zosonkhanitsira magazi a venous zogwiritsidwa ntchito kamodzi" (monga GB/T 19489-2008) kuwonetsetsa kuti sterility, non-pyrogenic and non-cytotoxicity ikugwira ntchito.

Mitundu yosiyanasiyana ya machubu otolera magazi a EDTA

Malinga ndi miyezo yapadziko lonse lapansi (monga malangizo a CLSI H3-A6), machubu osonkhanitsira magazi a EDTA nthawi zambiri amakhala ofiirira (EDTA-K2/K3) kapena buluu (sodium citrate wosakanikirana ndi EDTA) kuti asiyanitse kugwiritsa ntchito:

Zindikirani: Mitundu ina ikhoza kulembedwa mumitundu ina, fufuzani malangizo musanagwiritse ntchito.

Njira ya Anticoagulation ya machubu osonkhanitsira magazi a EDTA

EDTA kudzera mu gulu lake la molekyulu ya carboxyl (-COOH) ndi ayoni a calcium m'magazi (Ca²⁺) ophatikizidwa kuti apange chelate yokhazikika, motero amalepheretsa kuyambitsa kwa plasminogen, kutsekereza njira yolumikizana ya fibrinogen mu fibrin. Anticoagulation iyi ili ndi zotsatirazi:

1. Kuyamba mwachangu: anticoagulation imatha kutha mkati mwa mphindi 1-2 mutatolera magazi;

2. kukhazikika kwakukulu: zitsanzo zikhoza kusungidwa kwa maola oposa 48 (firiji ikhoza kupitilira maola 72);

3. Ntchito zambiri: zoyenera kuyesedwa kwa hematology, koma osati kuyesa kuyesa kwa coagulation kapena platelet (machubu a sodium citrate amafunikira).

Zinthu zazikulu zoyezera za chubu chotolera magazi cha EDTA

1. kusanthula magazi mwachizolowezi: kuchuluka kwa maselo oyera a magazi, magawo a maselo ofiira a magazi, kuchuluka kwa hemoglobini, ndi zina zotero;

2. Kuzindikiritsa gulu la magazi ndi kufananiza: Gulu la magazi la ABO, kuzindikira kwa Rh factor;

3. Kuzindikira kwa maselo: kuyezetsa majini, kudziwa kuchuluka kwa ma virus (monga HIV, HBV);

4. glycated hemoglobin (HbA1c): kuyang'anira shuga wamagazi kwa nthawi yayitali pa matenda a shuga;

5. kuyeza kwa tiziromboti ta magazi: Plasmodium, microfilariae kuzindikira.

Kugwiritsa ntchito zikhalidwe ndi zodzitetezera

1. Njira yosonkhanitsira:

Mukathira mankhwala pakhungu, gwirani ntchito molingana ndi muyezo wa venous magazi;

Mukangotenga, tembenuzani chubu chotolera magazi ka 5-8 kuti muwonetsetse kuti anticoagulant yasakanizidwa ndi magazi;

Pewani kugwedezeka kwamphamvu (kupewa hemolysis).

2. Kusunga ndi mayendedwe:

Sungani kutentha kwapakati (15-25 ° C), pewani kutentha kapena kuzizira;

Ikani molunjika panthawi yamayendedwe kuti mupewe kumasula kapu ya chubu.

3. contraindications zochitika:

Machubu a sodium citrate amafunikira kuti Coagulation IV (PT, APTT, etc.);

Kuyesa ntchito ya platelet kumafuna chubu cha sodium citrate.

Momwe mungasankhire khalidwe lapamwambachubu chotolera magazi cha EDTA?

1. Kuyenerera ndi certification: sankhani zinthu zomwe zadutsa ISO13485 ndi CE certification. 2;

2. Chitetezo cha zinthu: thupi la chubu liyenera kukhala lowonekera komanso lopanda zotsalira za plasticizer;

3. Dosing yolondola: kuchuluka kwa anticoagulant kuwonjezeredwa kuyenera kugwirizana ndi chikhalidwe cha dziko (mwachitsanzo EDTA-K2 ndende ya 1.8 ± 0.15mg / mL);

4. Mbiri ya Brand: Chofunika kwambiri chimaperekedwa kwa malonda odziwika bwino pazamankhwala kuti atsimikizire kukhazikika kwa batch.

Mapeto

Monga membala wofunikira wachipangizo chosonkhanitsira magazi, Machubu osonkhanitsira magazi a EDTA amakhudza mwachindunji kulondola kwa zotsatira za mayeso malinga ndi zomwe ali nazo anticoagulant. Mwa kulinganiza kugwiritsiridwa ntchito kwa machubu osonkhanitsira magazi okhala ndi mitundu yosiyanasiyana ndi kuwaphatikiza ndi njira zotsatirika zosonkhanitsira, kungapereke maziko odalirika a matenda. M'tsogolomu, ndi chitukuko cha mankhwala olondola, machubu otolera magazi a EDTA adzakhala ndi gawo lofunika kwambiri pakuwunika magazi, kutsata ma gene ndi madera ena, ndikupitiriza kuteteza thanzi la anthu.