Kodi Embolic Microspheres ndi chiyani?

Zizindikiro Zogwiritsira Ntchito (Fotokozani)

Ma Microspheres a Emboliccholinga chake ndi kugwiritsa ntchito pochotsa ma arteriovenous malformations (AVMs) ndi zotupa za hypervascular, kuphatikizapo uterine fibroids.

 

Dzina Lofala Kapena Lachizolowezi: Polyvinyl Alcohol Embolic Microspheres Classification

Dzina: Chipangizo Chothandizira Kutulutsa Mitsempha ya Mtima

Gulu: Kalasi Yachiwiri

Gulu: Mitsempha ya Mtima

 

Kufotokozera kwa Chipangizo

 

Ma Microspheres a Embolic ndi ma microspheres a hydrogel opanikizika okhala ndi mawonekedwe ofanana, pamwamba posalala, ndi kukula kolinganizidwa, omwe amapangidwa chifukwa cha kusintha kwa mankhwala pazinthu za polyvinyl alcohol (PVA). Ma Microspheres a Embolic ali ndi macromer ochokera ku polyvinyl alcohol (PVA), ndipo ndi okonda madzi, osasinthika, ndipo amapezeka m'mitundu yosiyanasiyana. Yankho losungira ndi 0.9% sodium chloride solution. Madzi a microsphere yopangidwa ndi polymer ndi 91% ~ 94%. Ma Microspheres amatha kupirira kupsinjika kwa 30%.

Ma Microspheres a Embolic amaperekedwa opanda poizoni ndipo amapakidwa m'mabotolo agalasi otsekedwa.

Ma Microspheres a Embolic apangidwa kuti agwiritsidwe ntchito pochotsa ma arteriovenous malformations (AVMs) ndi zotupa za hypervascular, kuphatikizapo uterine fibroids. Mwa kuletsa magazi kupita kudera lomwe likufunidwa, chotupacho kapena malformation sichikhala ndi michere yambiri ndipo kukula kwake kumachepa.

Ma Microspheres a Embolic amatha kuperekedwa kudzera mu ma microcatheters wamba omwe ali mu 1.7-4 Fr range. Panthawi yogwiritsidwa ntchito, Ma Microspheres a Embolic amasakanizidwa ndi nonionic contrast agent kuti apange suspension solution. Ma Microspheres a Embolic amapangidwira kugwiritsidwa ntchito kamodzi ndipo amaperekedwa opanda poizoni komanso osayambitsa pyrogenic. Mapangidwe a chipangizo cha Embolic Microsphere afotokozedwa mu Table 1 ndi Table 2 pansipa.

Pakati pa mitundu yosiyanasiyana ya kukula kwa Embolic Microspheres, mitundu yosiyanasiyana ya kukula yomwe ingagwiritsidwe ntchito pochotsa uterine fibroid ndi 500-700μm, 700-900μm ndi 900-1200μm.

Tebulo: Makonzedwe a chipangizo cha Embolic Microspheres
Chogulitsa Khodi	Yolinganizidwa Kukula (µm)	Kuchuluka	Chizindikiro
			Matenda a Mitsempha Yambiri/ Mitsempha Yambiri Zolakwika	Uterine Fibroid
B107S103	100-300	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	No
B107S305	300-500	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	No
B107S507	500-700	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	Inde
B107S709	700-900	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	Inde
B107S912	900-1200	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	Inde
B207S103	100-300	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	No
B207S305	300-500	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	No
B207S507	500-700	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	Inde
B207S709	700-900	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	Inde
B207S912	900-1200	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	Inde

 

Chogulitsa Khodi	Yolinganizidwa Kukula (µm)	Kuchuluka	Chizindikiro
			Matenda a Mitsempha Yambiri/ Mitsempha Yambiri Zolakwika	Uterine Fibroid
U107S103	100-300	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	No
U107S305	300-500	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	No
U107S507	500-700	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	Inde
U107S709	700-900	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	Inde
U107S912	900-1200	Ma microspheres a 1ml: 7ml 0.9% sodium chloride	Inde	Inde
U207S103	100-300	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	No
U207S305	300-500	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	No
U207S507	500-700	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	Inde
U207S709	700-900	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	Inde
U207S912	900-1200	Ma microspheres a 2ml: 7ml 0.9% sodium chloride	Inde	Inde