Kodi Embolic Microspheres ndi chiyani?

Zizindikiro Zogwiritsidwa Ntchito (Tafotokozani)

Embolic MicrospheresAmapangidwa kuti azigwiritsidwa ntchito poyambitsa matenda a arteriovenous malformations (AVMs) ndi zotupa za hypervascular, kuphatikizapo uterine fibroids.

 

Dzina lodziwika kapena lodziwika bwino: Gulu la Polyvinyl Alcohol Embolic Microspheres

Dzina: Vascular Embolization Device

Gulu: Gulu II

Gulu: Zamtima

 

Kufotokozera kwa Chipangizo

 

Embolic Microspheres ndi ma compressible hydrogel microspheres okhala ndi mawonekedwe okhazikika, osalala pamwamba, ndi kukula kwake, omwe amapangidwa chifukwa cha kusintha kwa mankhwala pa zida za polyvinyl mowa (PVA). Embolic Microspheres imakhala ndi macromer yochokera ku polyvinyl alcohol (PVA), ndipo ndi hydrophilic, yosasinthika, ndipo imapezeka mosiyanasiyana. Njira yothetsera vutoli ndi 0.9% sodium chloride solution. Madzi okhala ndi polymerized microsphere ndi 91% ~ 94%. Ma Microspheres amatha kulekerera kupsinjika kwa 30%.

Ma Embolic Microspheres amaperekedwa osabala ndipo amapakidwa mu mbale zagalasi zomata.

Embolic Microspheres adapangidwa kuti azigwiritsidwa ntchito popanga ma arteriovenous malformations (AVMs) ndi zotupa za hypervascular, kuphatikiza uterine fibroids. Mwa kutsekereza magazi kudera lomwe mukufuna, chotupacho kapena cholakwikacho chimakhala ndi njala yazakudya ndikuchepa kukula.

Embolic Microspheres imatha kuperekedwa kudzera mu ma microcatheter wamba mumtundu wa 1.7-4 Fr. Panthawi yogwiritsira ntchito, Embolic Microspheres imasakanizidwa ndi chinthu chosiyana ndi nonionic kuti apange yankho loyimitsidwa. Embolic Microspheres amapangidwa kuti azigwiritsidwa ntchito kamodzi ndipo amaperekedwa osabala komanso osakhala pyrogenic. Kukonzekera kwa chipangizo cha Embolic Microsphere akufotokozedwa mu Table 1 ndi Table 2 pansipa.

Pakati pa kukula kosiyanasiyana kwa Embolic Microspheres, kukula kwake komwe kungagwiritsidwe ntchito popanga uterine fibroid embolization ndi 500-700μm, 700-900μm ndi 900-1200μm.

Table: Kusintha kwa Chipangizo kwa Embolic Microspheres
Zogulitsa Kodi	Zolinganizidwa Kukula (µm)	Kuchuluka	Chizindikiro
			Hypervascular zotupa / Arteriovenous Zolakwika	Uterine Fibroid
B107S103	100-300	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	No
B107S305	300-500	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	No
B107S507	500-700	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
B107S709	700-900	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
B107S912	900-1200	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
B207S103	100-300	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	No
B207S305	300-500	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	No
B207S507	500-700	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
B207S709	700-900	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
B207S912	900-1200	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde

 

Zogulitsa Kodi	Zolinganizidwa Kukula (µm)	Kuchuluka	Chizindikiro
			Hypervascular zotupa / Arteriovenous Zolakwika	Uterine Fibroid
U107S103	100-300	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	No
U107S305	300-500	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	No
U107S507	500-700	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
U107S709	700-900	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
U107S912	900-1200	1ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
U207S103	100-300	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	No
U207S305	300-500	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	No
U207S507	500-700	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
U207S709	700-900	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde
U207S912	900-1200	2ml microspheres: 7ml 0.9% sodium kolorayidi	Inde	Inde