Chipangizo Chothandizira Kulimbitsa Mitsempha ya Mtima cha Polyvinyl Alcohol Embolic Microspheres

Zizindikiro Zogwiritsira Ntchito (Fotokozani)

Ma Microspheres a Emboliccholinga chake ndi kugwiritsa ntchito pochotsa ma arteriovenous malformations (AVMs) ndi zotupa za hypervascular, kuphatikizapo uterine fibroids.

Dzina Lodziwika Kapena Lachizolowezi:Ma Microspheres a Polyvinyl Alcohol EmbolicKugawa

Dzina:Chipangizo Chothandizira Kulimbitsa Mitsempha

Gulu: Kalasi Yachiwiri

Gulu:Matenda a mtima

Kufotokozera kwa Chipangizo

Ma Microspheres a Embolic ndi ma microspheres a hydrogel opanikizika okhala ndi mawonekedwe ofanana, pamwamba posalala, ndi kukula kolinganizidwa, omwe amapangidwa chifukwa cha kusintha kwa mankhwala pazinthu za polyvinyl alcohol (PVA). Ma Microspheres a Embolic ali ndi macromer ochokera ku polyvinyl alcohol (PVA), ndipo ndi okonda madzi, osasinthika, ndipo amapezeka m'mitundu yosiyanasiyana. Yankho losungira ndi 0.9% sodium chloride solution. Madzi a microsphere yopangidwa ndi polymer ndi 91% ~ 94%. Ma Microspheres amatha kupirira kupsinjika kwa 30%.

Ma Microspheres a Embolic amaperekedwa opanda poizoni ndipo amapakidwa m'mabotolo agalasi otsekedwa.

Ma Microspheres a Embolic apangidwa kuti agwiritsidwe ntchito pochotsa ma arteriovenous malformations (AVMs) ndi zotupa za hypervascular, kuphatikizapo uterine fibroids. Mwa kuletsa magazi kupita kudera lomwe likufunidwa, chotupacho kapena malformation sichikhala ndi michere yambiri ndipo kukula kwake kumachepa.

Ma Microspheres a Embolic amatha kuperekedwa kudzera mu ma microcatheters wamba omwe ali mu 1.7-4 Fr range. Panthawi yogwiritsidwa ntchito, Ma Microspheres a Embolic amasakanizidwa ndi nonionic contrast agent kuti apange suspension solution. Ma Microspheres a Embolic amapangidwira kugwiritsidwa ntchito kamodzi ndipo amaperekedwa opanda poizoni komanso osayambitsa pyrogenic. Mapangidwe a chipangizo cha Embolic Microsphere afotokozedwa mu Table 1 ndi Table 2 pansipa.

Pakati pa mitundu yosiyanasiyana ya kukula kwa Embolic Microspheres, mitundu yosiyanasiyana ya kukula yomwe ingagwiritsidwe ntchito pochotsa uterine fibroid ndi 500-700μm, 700-900μm ndi 900-1200μm.

Table: Makonzedwe a chipangizo cha Embolic Microspheres

Ichizindikiro

Pronjira yodutsa mpweya

Khodi

Yolinganizidwa

Kukula (µm)

Quantity

HyZotupa za m'mitsempha yamagazi/ Mitsempha ya m'mitsempha

Mamapangidwe

Uterine Fibroid

B107S103 100-300

Ma microspheres a 1ml: 7ml 0.9%

sodium chloride

Inde Ayi

B107S305 300-500

Ma microspheres a 1ml: 7ml 0.9%

sodium chloride

Inde Ayi

B107S507 500-700

Ma microspheres a 1ml: 7ml 0.9%

sodium chloride

Inde Inde

B107S709 700-900

Ma microspheres a 1ml: 7ml 0.9%

sodium chloride

Inde Inde

B107S912 900-1200

Ma microspheres a 1ml: 7ml 0.9%

sodium chloride

Inde Inde

B207S103 100-300

Ma microspheres a 2ml: 7ml 0.9%

sodium chloride

Inde Ayi

B207S305 300-500

Ma microspheres a 2ml: 7ml 0.9%

sodium chloride

Inde Ayi

B207S507 500-700

Ma microspheres a 2ml: 7ml 0.9%

sodium chloride

Inde Inde

B207S709 700-900

Ma microspheres a 2ml: 7ml 0.9%

sodium chloride

Inde Inde

B207S912 900-1200

Ma microspheres a 2ml: 7ml 0.9%

sodium chloride

Inde Inde